Tet\u00eb foshnje jan\u00eb lindur n\u00eb Mbret\u00ebrin\u00eb e Bashkuar duke p\u00ebrdorur nj\u00eb teknik\u00eb t\u00eb avancuar q\u00eb p\u00ebrfshin material gjenetik nga tre persona t\u00eb ndrysh\u00ebm, me q\u00ebllimin p\u00ebr t\u00eb parandaluar s\u00ebmundje mitokondriale t\u00eb r\u00ebnda dhe shpesh fatale, b\u00ebjn\u00eb t\u00eb ditur mjek\u00ebt britanik\u00eb.
Metoda, e zhvilluar nga shkenc\u00ebtar\u00eb n\u00eb Mbret\u00ebrin\u00eb e Bashkuar, kombinon vez\u00ebn dhe sperm\u00ebn nga prind\u00ebrit biologjik\u00eb me nj\u00eb vez\u00eb t\u00eb dyt\u00eb nga nj\u00eb grua dhuruese. Teknik\u00ebs i \u00ebsht\u00eb dh\u00ebn\u00eb statusi ligjor n\u00eb vend q\u00eb prej nj\u00eb dekade, por tashm\u00eb \u00ebsht\u00eb konfirmuar se ajo \u00e7on n\u00eb lindjen e f\u00ebmij\u00ebve t\u00eb sh\u00ebndetsh\u00ebm, t\u00eb lir\u00eb nga k\u00ebto s\u00ebmundje t\u00eb pash\u00ebrueshme.<\/p>\n\n\n\n
S\u00ebmundjet mitokondriale trash\u00ebgohen zakonisht nga n\u00ebna dhe pengojn\u00eb trupin t\u00eb prodhoj\u00eb energjin\u00eb e nevojshme p\u00ebr jetes\u00eb. Kjo munges\u00eb energjie mund t\u00eb shkaktoj\u00eb paaft\u00ebsi t\u00eb r\u00ebnda, d\u00ebmtime t\u00eb trurit, verb\u00ebri, d\u00ebshtim t\u00eb organeve dhe shpesh vdekje t\u00eb foshnj\u00ebs brenda dit\u00ebve t\u00eb para pas lindjes.
F\u00ebmij\u00ebt e lindur p\u00ebrmes k\u00ebsaj metode trash\u00ebgojn\u00eb shumic\u00ebn e ADN-s\u00eb nga prind\u00ebrit e tyre (rreth 99.9%), por marrin edhe nj\u00eb sasi shum\u00eb t\u00eb vog\u00ebl (rreth 0.1%) t\u00eb ADN-s\u00eb nga dhuruesja, konkretisht mitokondrit\u00eb e saj t\u00eb sh\u00ebndetshme \u2013 nj\u00eb ndryshim q\u00eb mund t\u00eb p\u00ebrcillet brez pas brezi.
Familjet q\u00eb kan\u00eb kaluar n\u00ebp\u00ebr k\u00ebt\u00eb proces kan\u00eb zgjedhur t\u00eb mbeten anonime p\u00ebr t\u00eb ruajtur privat\u00ebsin\u00eb e tyre, por kan\u00eb dh\u00ebn\u00eb deklarata p\u00ebrmes Qendr\u00ebs s\u00eb Fertilitetit n\u00eb Newcastle, ku edhe jan\u00eb kryer procedurat.
Nj\u00eb n\u00ebn\u00eb q\u00eb ka lindur nj\u00eb vajz\u00eb p\u00ebrmes k\u00ebsaj metode ka th\u00ebn\u00eb:<\/p>\n\n\n\n
\u201cPas viteve me pasiguri, kjo trajtim na dha shpres\u00eb \u2013 dhe m\u00eb pas na dha vajz\u00ebn ton\u00eb. E shohim sot, plot jet\u00eb dhe mund\u00ebsi, dhe jemi t\u00eb mbushur me mir\u00ebnjohje.\u201d
Nd\u00ebrsa n\u00ebna e nj\u00eb djali shtoi:
\u201cFal\u00eb k\u00ebtij p\u00ebrparimi t\u00eb jasht\u00ebzakonsh\u00ebm dhe mb\u00ebshtetjes q\u00eb mor\u00ebm, familja jon\u00eb e vog\u00ebl \u00ebsht\u00eb m\u00eb n\u00eb fund e plot\u00eb. Barr\u00ebn emocionale t\u00eb s\u00ebmundjes mitokondriale e ka z\u00ebvend\u00ebsuar shpresa, g\u00ebzimi dhe nj\u00eb mir\u00ebnjohje e thell\u00eb.\u201d
Mitokondrit\u00eb jan\u00eb struktura mikroskopike brenda pothuajse \u00e7do qelize t\u00eb trupit, q\u00eb p\u00ebrdorin oksigjenin p\u00ebr t\u00eb kthyer ushqimin n\u00eb energji. Kur ato jan\u00eb t\u00eb d\u00ebmtuara, trupi nuk merr energjin\u00eb e nevojshme p\u00ebr funksione jetike si rrahjet e zemr\u00ebs apo aktiviteti i trurit.<\/p>\n\n\n\n
Rreth nj\u00eb n\u00eb 5,000 foshnje lindin me s\u00ebmundje mitokondriale. Ekipi n\u00eb Newcastle parashikon nj\u00eb nevoj\u00eb prej 20 deri n\u00eb 30 lindje t\u00eb tilla n\u00eb vit p\u00ebrmes k\u00ebsaj metode.
P\u00ebr shum\u00eb prind\u00ebr, kjo teknologji ka ardhur pas p\u00ebrvoj\u00ebs s\u00eb dhimbshme t\u00eb humbjes s\u00eb f\u00ebmij\u00ebve t\u00eb tjer\u00eb p\u00ebr shkak t\u00eb k\u00ebsaj s\u00ebmundjeje. Si mitokondrit\u00eb trash\u00ebgohen vet\u00ebm nga n\u00ebna, teknika p\u00ebrdor vez\u00ebt e n\u00ebn\u00ebs dhe t\u00eb nj\u00eb dhuruese me mitokondri t\u00eb sh\u00ebndetshme.
Shkenca q\u00ebndron prapa nj\u00eb procesi t\u00eb nd\u00ebrlikuar laboratorik, ku vez\u00ebt nga n\u00ebna dhe dhuruesja fertilizohen me sperm\u00ebn e babait. ADN-ja kryesore nga prind\u00ebrit ruhet, nd\u00ebrsa mitokondrit\u00eb e dhuruara mbeten p\u00ebr t\u00eb siguruar sh\u00ebndetin qelizor t\u00eb foshnj\u00ebs.
Kjo arritje, zhvilluar n\u00eb Universitetin e Newcastle dhe n\u00eb sistemin spitalor NHS, p\u00ebrfaq\u00ebson nj\u00eb p\u00ebrparim t\u00eb madh n\u00eb fush\u00ebn e mjek\u00ebsis\u00eb gjenetike dhe fertilitetit.<\/p>\n","protected":false},"excerpt":{"rendered":"
Tet\u00eb foshnje jan\u00eb lindur n\u00eb Mbret\u00ebrin\u00eb e Bashkuar duke p\u00ebrdorur nj\u00eb teknik\u00eb t\u00eb avancuar q\u00eb p\u00ebrfshin material gjenetik nga tre persona t\u00eb ndrysh\u00ebm, me q\u00ebllimin p\u00ebr t\u00eb parandaluar s\u00ebmundje mitokondriale t\u00eb r\u00ebnda dhe shpesh fatale, b\u00ebjn\u00eb t\u00eb ditur mjek\u00ebt britanik\u00eb. Metoda, e zhvilluar nga shkenc\u00ebtar\u00eb n\u00eb Mbret\u00ebrin\u00eb e Bashkuar, kombinon vez\u00ebn dhe sperm\u00ebn nga prind\u00ebrit […]<\/p>\n","protected":false},"author":2,"featured_media":61201,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28],"tags":[],"class_list":{"0":"post-61202","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-lifestyle"},"yoast_head":"\n